Lab Publications 
  1. Lee DG*, McLachlan CA*, Nogueira R, Kwon O, Carey AE, House G, Lagani GD, LaMay D, Fusi S, Chen JL. Perirhinal cortex learns a predictive map of the task environment. Nat Commun. 2024 Jul 2;15(1):5544. doi: 10.1038/s41467-024-47365-7. (pdf)
  2. Platisa J*, Ye X*, Ahrens AM, Liu C, Chen IA, Davison IG, Tian L, Pieribone VA, Chen JL. High-speed low-light in vivo two-photon voltage imaging of large neuronal populations. Nat Methods. 2023: 10.1038/s41592-023-01820-3. (pdf)
  3. Condylis C, Ghanbari A, Manjrekar N, Bistrong K, Yao SQ, Yao ZZ, Nguyen TN, Zeng HK, Tasic B, Chen JL. Dense functional and molecular readout of a circuit hub in sensory cortex. Science. 2022 Jan 7;375(6576):eabl5981. (pdf)
  4. Clough M, Chen IA, Park SW, Ahrens AM, Stirman JN, Smith SL, Chen JL. Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds. Nat Commun. 2021 Nov 17; 12:6638. (pdf)
  5. Mohr MA, Bushey D, Aggarwal A, Marvin JS, Kim JJ, Marquez EJ, Liang Y, Patel R, Macklin JJ, Lee CY, Tsang A, Tsegaye G, Ahrens AM, Chen JL, Kim DS, Wong AM, Looger LL, Schreiter ER, Podgorski K. jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths. Nat Methods. 2020 Jul;17(7):694-697. 
  6. Condylis C*, Lowet E*, Ni J, Bistrong K, Ouellette T, Josephs N, Chen JL. Context dependent sensory processing across primary and secondary somatosensory cortex. Neuron. 2020 May 6;106(3):515-525.e5. *Equal contribution (pdf)
  7. Clough M, Chen JL. Cellular resolution imaging of neuronal activity across space and time in the mammalian brain. Curr Opin Biomed Eng. 2019 Dec;12:95-101. (pdf)
  8. Ni J, Chen JL. Long-range cortical dynamics: a perspective from the mouse sensorimotor whisker system. Eur J Neurosci.  2017 Oct;46(8):2315-2324. (pdf)

Previous Publications
  1. Helmchen F, Gilad A, Chen JL. Neocortical dynamics during whisker-based sensory discrimination in head-restrained mice. Neuroscience. 2018 Jan 1;368:57-69. 
  2. Bethge P, Carta S, Lorenzo DA, Egolf L, Goniotaki D, Madisen L, Voigt FF, Chen JL, Schneider B, Ohkura M, Nakai J, Zeng H, Aguzzi A, Helmchen F.  An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator.  PLoS One. 2017 Jun 22;12(6):e0179460.
  3. Chen JL*, Voigt F*, Javadzadeh M, Kruppel R, Helmchen F. Long-range population dynamics of anatomically defined neocortical networks.  eLife. 2016 May 24;5. pii: e14679. *Equal contribution (pdf)
  4. Helmchen F, Chen JL. Imaging the cortical representation of active sensing in the vibrissa system. Sensorimotor Integration in the Whisker System. Springer, 2015:109-128. 
  5. Chen JL, Margolis DJ, Stankov A, Sumanovski LT, Schneider BL, Helmchen F. Pathway-specific reorganization of projection neurons in somatosensory cortex during learning.  Nat Neurosci. 2015 Aug;18(8):1101-1108. (pdf)
  6. Chen JL, Nedivi E. Highly specific structural plasticity of inhibitory circuits in the adult cortex. Neuroscientist. 2013 Aug;19(4):384-393.
  7. Wahl AS, Omlor W, Rubio JC, Chen JL, Zheng H, Schroter A, Gullo M, Weinmann O, Kobayashi K, Helmchen F, Ommer B, Schwab ME. Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke. Science.2014 Jun 13;344(6189):1250-5.
  8. Chen JL*, Pfaffli O*, Voigt F, Margolis DJ, Helmchen F. Online correction of licking-induced brain motion during two-photon imaging with a tunable lens.  J Physiol. 2013 Oct 1;591(19):4689-4698.  *Equal contribution (pdf)
  9. Chen JL, Andermann ML, Keck T, Xu NL, Ziv Y. Imaging neuronal populations in behaving rodents: paradigms for studying neural circuits underlying behavior in the mammalian cortex. J Neurosci. 2013 Nov 6;33(45):17631-40. (pdf)
  10. Chen JL, Carta S, Soldado-Magraner J, Schneider BL, Helmchen F. Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex. Nature. 2013 Jul 18;499(7458):336-380. (pdf)
  11. Chen JL, Villa KL, Cha JW, So PT, Kubota Y, Nedivi E. Clustered inhibitory synapse and dendritic spine dynamics in the adult cortex. Neuron. 2012 Apr 26;74(2):361-73.
  12. Fujino T, Leslie JH, Eavri R, Chen JL, Lin WC, Flanders GH, Borok E, Horvath TL, Nedivi E.  CPG15 regulates synapse stability in the developing and adult brain. Genes Dev. 2011 Dec 15;25(24):2674-85.
  13. Chen JL, Flanders GH, Lee WC, Lin WC, Nedivi E. Inhibitory dendrite dynamics as a general feature of the adult cortical microcircuit. J Neurosci. 2011 Aug 31;31(35):12437-43.
  14. Chen JL, Lin WC, Cha JW, So PT, Kubota Y, Nedivi E. Structural basis for the role of inhibition in facilitating adult brain plasticity. Nat Neurosci. 2011 May;14(5):587-94.
  15. Chen JL, Nedivi E. Neuronal structural remodeling: is it all about access? Curr Opin Neurobiol. 2010 Oct;20(5):557-62. 
  16. Lee WC, Chen JL, Huang H, Leslie JH, Amitai Y, So PT, Nedivi E. A dynamic zone defines interneuron remodeling in the adult neocortex. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19968-73. 
  17. Chen JL, Peacock E, Samady W, Turner SM, Neese RA, Hellerstein MK, Murphy EJ. Physiologic and pharmacologic factors influencing glyceroneogenic contribution to triacylglyceride glycerol measured by mass isotopomer distribution analysis. J Biol Chem. 2005 Jul 8;280(27):25396-402.